Trabectedin (Ecteinascidin 743, ET-743) is a tetrahydroisoquinoline alkaloid that binds to the minor groove of DNA, blocks stress-induced transcription of proteins, induces DNA backbone cleavage and apoptosis, and increases ROS production in MCF-7 and MDA-MB-453 cells. Trabectedin can be used in soft tissue sarcoma and ovarian cancer studies.
Molecular Weight:
761.84
Purity:
>99%
CAS Number:
[114899-77-3]
Formula:
C39H43N3O11S
Target:
ROS
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