Zetomipzomib (KZR-616) maleate is a first-in-class inhibitor of immunoproteasome that selectively targets the immunoproteasome subunit LMP7 (IC50: 39/57 nM=hLMP7/mLMP7) and LMP2 (IC50:131/179 nM=hLMP7/mLMP7). Potential of Zetomipzomib maleate for use in multiple autoimmune diseases.
Molecular Weight:
702.75
Purity:
>99%
CAS Number:
[2170983-62-5]
Formula:
C34H46N4O12
Target:
Proteasome
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