Carfilzomib (PR-171) is an irreversible proteasome inhibitor with an IC50 of <5 nM. Carfilzomib irreverently selectively binds to the active site containing n-terminal threonine of the 20S proteasome and proteolytic core particles of the 26S proteasome.*The compound is unstable in solutions, freshly prepared is recommended.
Molecular Weight:
719.91
Purity:
>99.0%
CAS Number:
[868540-17-4]
Formula:
C40H57N5O7
Target:
Proteasome
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