BI-0474 is a covalent KRASG12C inhibitor. The IC50 value for GDP-KRAS::SOS1 protein-protein interaction was 7.0 nM. BI-0474 also showed better antitumor activity in non-small cell lung cancer xenograft models.
Molecular Weight:
587.74
Purity:
>99%
CAS Number:
[2750570-55-7]
Formula:
C30H37N9O2S
Target:
Ras
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