(+)-JQ1 is a BET bromodomain inhibitor that acts on BRD4(2) with an IC50 of 33 nM and binds to all bromodomain domains in the BET family, but not to bromodomain domains outside the BET family. JQ1 down-regulates CD47 expression through a C-MYC-mediated pathway, and JQ1 down-regulates CD47 expression through a C-MYC-mediated pathway.
Molecular Weight:
456.99
Purity:
>99.0%
CAS Number:
[1268524-70-4]
Formula:
C23H25ClN4O2S
Target:
Epigenetic Reader Domain
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