Felezonexor (CBS9106, SL-801) is a novel reversible oral CRM1 inhibitor with CRM1 degrading activity without affecting CRM1 mRNA levels. Felezonexor is also a reversible inhibitor of XPO1, inhibits nuclear export by covalently binding to Cys528 as well as by inducing the degradation of XPO1.
Molecular Weight:
419.83
Purity:
>99.0%
CAS Number:
[1076235-04-5]
Formula:
C18H21ClF3N3O3
Target:
CRM1
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