Camptothecin (CPT), an alkaloid, is an inhibitor of DNA Topoisomerase I (Topo I) with an IC50 value of 679 nM. Camptothecin (CPT) has strong antitumor activity against colorectal cancer, breast cancer, lung cancer and ovarian cancer, and modulates hypoxia-inducible factor-1alpha (HIF-1alpha) activity by altering miRNA expression patterns in human cancer cells.
Molecular Weight:
348.36
Purity:
99.88%
CAS Number:
[7689-03-4]
Formula:
C20H16N2O4
Target:
Topoisomerase
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