Thalidomide is a sedative and immunomodulator used to study the symptoms of many cancers, it has immunomodulatory, anti-inflammatory and anti-angiogenic cancer properties. Thalidomide inhibits cereblon (CRBN), a part of the cullin-4 E3 ubiquitin ligase complex CUL4-RBX1-DDB1, with a Kd of 250 nM.
Molecular Weight:
258.23
Purity:
99.81%
CAS Number:
[50-35-1]
Formula:
C13H10N2O4
Target:
Ligand for E3 Ligase
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