Capivasertib (AZD5363) is a potentially first-in-class, orally effective pan-AKT inhibitor with strong inhibition against all three AKT isomers (AKT1/2/3) at an IC50 of 3 nM/8 nM/8 nM. It also showed similar inhibitory effect on P70S6K/PKA and low inhibitory activity on ROCK1/2.
Molecular Weight:
428.92
Purity:
99.25%
CAS Number:
[1143532-39-1]
Formula:
C21H25ClN6O2
Target:
Akt
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