Pirfenidone (AMR69) is an antifibrotic agent that attenuates CCL2 and CCL12 production in fibrocyte cells. Pirfenidone inhibits TGF-beta bioactivity by affecting TGF-beta2 mRNA expression and processing of pro-TGF-beta in CCL-64 cells. Pirfenidone (AMR69) attenuates CCL2 and CCL12 production in fibrocyte cells.
Molecular Weight:
185.22
Purity:
99.93%
CAS Number:
[53179-13-8]
Formula:
C12H11NO
Target:
TGF-beta/Smad
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