GANT61 is a Gli1 and Gli2 inhibitor targeting the Hedgehog/GLi pathway that inhibits GLI1- and GLI2-induced transcription with an IC50 of 5 µM. In addition, GANT61 selectively acts on the transcription of other pathways such as TNF and glucocorticoid receptor genes.
Molecular Weight:
429.6
Purity:
99.66%
CAS Number:
[500579-04-4]
Formula:
C27H35N5
Target:
Gli
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