Dalotuzumab, CAS [[1005389-60-5]]

Product Overview

• Article Name: Dalotuzumab, CAS [[1005389-60-5]]
• Biozol Catalog Number: AMO-M24531
• Supplier Catalog Number: M24531
• Alternative Catalog Number: AMO-M24531-100UG, AMO-M24531-1MG
• Manufacturer: Abmole Bioscience
• Category: Biochemikalien

Product Description

Dalotuzumab (MK-0646) is a recombinant humanized monoclonal antibody (IgG1 type) targeting IGF-1R. Dalotuzumab acts by inhibiting IGF-1- and IGF-2-mediated tumor cell proliferation, IGF-1R autophosphorylation, and Akt phosphorylation. Dalotuzumab also induces apoptosis and cycle arrest. Dalotuzumab in combination with other anticancer drugs such as statins can enhance the antitumor activity of Dalotuzumab in vitro and in vivo.

Product Properties

• Purity: >97.0%
• CAS Number: [1005389-60-5]