Emapalumab (NI-0501) is a humanized monoclonal IgG1 antibody that noncompetitively inhibits IFN-gamma. Emapalumab binds with high affinity (Kd= 1.4 pM) to both free IFN-gamma as well as IFN-gamma bound to its receptor. Emapalumab can be used in research of hemophagocytic lymphohistiocytosis (HLH).
CAS Number:
[1709815-23-5]
Target:
Interferon-alpha/beta/gamma
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