Ontamalimab (SHP647) human IgG2 anti-MAdCAM-1 monoclonal antibody specifically blocks the binding of alpha4beta7 integrins to human mucosal addressin adhesion molecule-1 (MAdCAM1) ligand, thereby decreasing the migration of lymphocytes into the intestine. Ontamalimab may be used in studies related to ulcerative colitis (UC).
Purity:
>95.0%
CAS Number:
[2098790-40-8]
Target:
Others
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