GSK-J1 is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A, with IC50 of 60 nM towards KDM6B. GSK J1 is selective for the H3K27 demethylases JMJD3 and UTX.
Molecular Weight:
389.45
Purity:
99.94%
CAS Number:
[1373422-53-7]
Formula:
C22H23N5O2
Target:
Histone demethylase
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