Pyridostatin (RR82) is a G-quadruplex DNA stabilizing agent (Kd=490 nM). Pyridostatin promotes growth arrest in human cancer cells by inducing replication- and transcription-dependent DNA damage. Pyridostatin targets the proto-oncogene Src. Pyridostatin reduced SRC protein levels and SRC-dependent cellular motility in human breast cancer cells.
Molecular Weight:
596.64
Purity:
99.0%
CAS Number:
[1085412-37-8]
Formula:
C31H32N8O5
Target:
DNA/RNA Synthesis
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