IXA4 is a highly selective, non-toxic IRE1/XBP1s activator. IXA4 activates IRE1/XBP1s signaling without globally activating the unfolded protein response (UPR) or other stress-responsive signaling pathways (e.g., the heat shock response or oxidative stress response). IXA4 reduces secretion of APP through IRE1 activation.
Molecular Weight:
436.5
Purity:
99.0%
CAS Number:
[1185329-96-7]
Formula:
C24H28N4O4
Target:
IRE1
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