Tenapanor (AZD1722) hydrochloride is a first-in-class, potent, orally active sodium/hydrogen exchange isomer 3 (NHE3) inhibitor that reduces intestinal phosphate absorption primarily by decreasing passive paracellular phosphate flux. Tenapanor hydrochloride reduces intestinal absorption of phosphate by reducing passive paracellular phosphate flux. Tenapanor hydrochloride is used in studies related to chronic renal insufficiency, hyperphosphatemia, constipation, and irritable bowel syndrome.
Molecular Weight:
1217.97
Purity:
98.0%
CAS Number:
[1234365-97-9]
Formula:
C50H68Cl6N8O10S2
Target:
Na+/H+ Exchanger (NHE)
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