Ilginatinib hydrochloride (NS-018 hydrochloride) is a highly active and orally bioavailable JAK2 inhibitor, with an IC50 of 0.72 nM, 46-, 54-, and 31-fold selectivity for JAK2 over JAK1 (IC50, 33 nM), JAK3 (IC50, 39 nM), and Tyk2 (IC50, 22 nM).
Molecular Weight:
425.89
Purity:
98.5%
CAS Number:
[1239358-85-0]
Formula:
C21H21ClFN7
Target:
JAK
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