LDN-193189 dihydrochloride is a selective BMP signaling inhibitor, and inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 of 5 nM and 30 nM, respectively, 200-fold selectivity for BMP versus TGF-beta.
Molecular Weight:
479.40
Purity:
100.00%
CAS Number:
[1435934-00-1]
Formula:
C25H24Cl2N6
Target:
ALK
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