Macozinone (PBTZ169) is a bactericidal benzothiazinone and a potent DprE1 (decaprenylphosphoryl-beta-d-ribose 2'-oxidase) inhibitor. Macozinone inhibits the essential flavoprotein DprE1 by forming a covalent bond with the active-site Cys387 residue. Macozinone has antituberculosis effect.
Molecular Weight:
456.48
Purity:
99.0%
CAS Number:
[1377239-83-2]
Formula:
C20H23F3N4O3S
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