GSK-A1 is a selective type III phosphatidylinositol 4-kinase PI4KA (PI4KIIIalpha) inhibitor with a pIC50 of 8.5-9.8. GSK-A1 inhibits PtdIns(4,5)P2 resynthesis with an IC50 of about 3 nM. GSK-A1 potently decreases the levels of PtdIns(4)P with a negligible effect on PtdIns(4,5)P2. GSK-A1 has the potential for anti-hepatitis C virus (HCV) research.
Molecular Weight:
574.63
Purity:
98.5%
CAS Number:
[1416334-69-4]
Formula:
C29H27FN6O4S
Target:
PI3K
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