MM-401 (TFA) is a MLL1 H3K4 methyltransferase inhibitor. MM-401 inhibits MLL1 activity (IC50 = 0.32 µM) by blocking MLL1-WDR5 interaction. MM-401 can induce cell cycle arrest, apoptosis and differentiation. MM-401 can be used for the research of MLL leukemia.
Molecular Weight:
700.75
Purity:
99.0%
CAS Number:
[1442106-11-7]
Formula:
C31H47F3N8O7
Target:
Histone Methyltransferase
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