L-745870 is a potent, selective, brain-penetrant and orally active dopamine D4 receptor antagonist with a Ki of 0.43 nM. L-745870 shows weaker affinity for D2 (Ki of 960 nM) and D3 (Ki of 2300 nM) receptors, and exhibits moderate affinity for 5-HT2 receptors, sigma sites and alpha-adrenoceptors.
Molecular Weight:
326.82
Purity:
99.0%
CAS Number:
[158985-00-3]
Formula:
C18H19ClN4
Target:
Dopamine Receptor
* VAT and and shipping costs not included. Errors and price changes excepted
