AMG PERK 44 is an orally active and highly selective PERK inhibitor with an IC50 of 6 nM. AMG PERK 44 has 1000-fold and 160-fold selectivity over GCN2 (IC50=7300 nM) and B-Raf (IC50 >1000 nM), respectively. AMG PERK 44 induces autophagy.
Molecular Weight:
561.07
Purity:
99.0%
CAS Number:
[1883548-84-2]
Formula:
C34H29ClN4O2
Target:
PERK
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