SLM6031434 hydrochloride is a highly selective sphingosine kinase 2 (SphK2) inhibitor with Kis of 0.4 µM, 0.5 µM, >20 µM, 22 µM for mSphK2, rSphK2, mSphK1 and rSphK1, respectively. SLM6031434 hydrochloride decrease Sphingosine 1-phosphate (S1P) levels in U937 monocytic leukemia cells. SLM6031434 hydrochloride has the potential for renal fibrosis research.
Molecular Weight:
489.96
CAS Number:
[1897379-34-8]
Formula:
C22H31ClF3N5O2
Target:
SPHK
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