BOLD-100 (NKP-1339, IT-139) is the first-in-class ruthenium-based anticancer agent in development against solid cancer with limited side effects. BOLD-100 induces G2/M cell cycle arrest, blockage of DNA synthesis, and induction of apoptosis via the mitochondrial pathway. BOLD-100 has a high tumor targeting potential, strongly binds to serum proteins such as albumin and transferrin and activates in the reductive tumor milieu.
Molecular Weight:
502.14
Purity:
99.0%
CAS Number:
[197723-00-5]
Formula:
C14H12Cl4N4NaRu
Target:
DNA/RNA Synthesis
* VAT and and shipping costs not included. Errors and price changes excepted
