JNJ-61432059, CAS [[2035814-50-5]]

Product Overview

• Article Name: JNJ-61432059, CAS [[2035814-50-5]]
• Biozol Catalog Number: AMO-M29120
• Supplier Catalog Number: M29120
• Alternative Catalog Number: AMO-M29120-1MG,AMO-M29120-5MG,AMO-M29120-10MG,AMO-M29120-25MG
• Manufacturer: Abmole Bioscience
• Category: Biochemikalien

Product Description

JNJ-61432059 is an oral active and selective negative modulator of AMPAR associated with trans-membrane AMPAR regulatory protein (TARP) gamma-8, with a pIC50 of 9.7 for GluA1/gamma-8. Exhibits time- and dose-dependent AMPAR/gamma-8 receptor occupancy in mouse hippocampus, resulting in robust seizure protection in corneal kindling and pentylenetetrazole (PTZ) anticonvulsant models.

Product Properties

• Molecular Weight: 443.47
• Purity: 99.0%
• CAS Number: [2035814-50-5]
• Formula: C25H22FN5O2
• Target: GluR