BMS-1166 hydrochloride is a potent PD-1/PD-L1 immune checkpoint inhibitor. BMS-1166 hydrochloride induces dimerization of PD-L1 and blocks its interaction with PD-1, with an IC50 of 1.4 nM. BMS-1166 hydrochloride antagonizes the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation.
Molecular Weight:
677.57
Purity:
99.0%
CAS Number:
[2113650-05-6]
Formula:
C36H34Cl2N2O7
Target:
PD-1/PD-L1
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