SU16f is a potent and selective PDGFRbeta inhibitor with IC50s of 10 nM, 140 nM, 2.29 µM for PDGFRbeta, PDGFR1, PDGFR2, respectively. Neutralization of PDGFRbeta receptor by SU16f blocks the promoting role of GC-MSCs (gastric cancer-derived mesenchymal stem cells) conditioned medium in gastric cancer cell proliferation and migration.
Molecular Weight:
386.44
Purity:
99.0%
CAS Number:
[251356-45-3]
Formula:
C24H22N2O3
Target:
VEGFR/PDGFR
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