GSK3987 is a pan LXRalpha/beta agonist with EC50s of 50 nM, 40 nM for LXRalpha-SRC1 and LXRbeta-SRC1, respectively. GSK3987 increases the expression of ABCA1 and SREBP-1c. GSK3987 induces cellular cholesterol efflux and triglyceride accumulation.
Molecular Weight:
384.43
Purity:
99.0%
CAS Number:
[264206-85-1]
Formula:
C24H20N2O3
Target:
Liver X Receptor
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