Ro 31-8220 is a pan-PKC inhibitor with IC50 of 5 nM, 24 nM, 14 nM, 27 nM, and 24 nM for PKC-alpha, PKC-betaI, PKC-betaII, PKC-gamma, and PKC-epsilon, respectively, and also shows potent inhibition against MAPKAP-K1b, MSK1, GSK3beta and S6K1.
Molecular Weight:
553.65
Purity:
>99.0%
CAS Number:
[138489-18-6]
Formula:
C25H23N5O2S.CH4O3S
Target:
PKC
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