NU6102 is a potent CDK1 and CDK2 inhibitor with IC50s of 9.5 nM and 5.4 nM for CDK1/cyclinB and CDK2/cyclinA3, respectively. NU6102 shows selectivity for CDK1/CDK2 over CDK4 (IC50 of 1.6 µM), DYRK1A (IC50 of 0.9 µM), PDK1 (IC50 of 0.8 µM) and ROCKII (IC50 of 0.6 µM).
Molecular Weight:
402.47
Purity:
99.0%
CAS Number:
[444722-95-6]
Formula:
C18H22N6O3S
Target:
CDK
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