NH-3 is an orally active, reversible thyroid hormone receptor (THR) antagonist with an IC50 of 55 nM. NH-3, a derivative of the selective thyromi-metic GC-1, inhibits binding of thyroid hormones to their receptor and that inhibits cofactor recruitment.
Molecular Weight:
473.52
Purity:
99.0%
CAS Number:
[447415-26-1]
Formula:
C28H27NO6
Target:
Thyroid Hormone Receptor
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