Dantrolene (F368) non-competitively inhibits human erythrocyte glutathione reductase. Ki and IC50 values are 111.6 µM and 52.3 µM, respectively. Dantrolene is a ryanodine receptor antagonist and Ca2+ signaling stabilizer. Dantrolene can be used for the research of muscle spasticity, malignant hyperthermia, Huntingtons disease and other neuroleptic malignant syndrome.
Molecular Weight:
314.25
Purity:
99.0%
CAS Number:
[7261-97-4]
Formula:
C14H10N4O5
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