ML291 is a first-in-class, potent chemical probe with an EC50 value of 762 nM that selectively activates the PERK/eIF2a/CHOP (apoptosis) arm of the unfolded protein response (UPR) and induces apoptosis in a variety of solid cancer models for leukemia-related studies.
Molecular Weight:
413.83
Purity:
>98.0%
CAS Number:
[1523437-16-2]
Formula:
C16H16ClN3O6S
Target:
PERK
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