Bisindolylmaleimide VIII acetate (Ro 31-7549 acetate) is a potent and selective protein kinase C (PKC) inhibitor with an IC50 of 158 nM for rat brain PKC. Bisindolylmaleimide VIII acetate has IC50s of 53, 195, 163, 213, and 175 nM for PKC-alpha, PKC-betaI, PKC-betaII, PKC-gamma, PKC-epsilon, respectively.
Molecular Weight:
458.51
Purity:
99.0%
CAS Number:
[138516-31-1]
Formula:
C26H26N4O4
Target:
PKC
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