BMSpep-57 hydrochloride, CAS [[1629655-80-6 free base]]

Product Overview

• Article Name: BMSpep-57 hydrochloride, CAS [[1629655-80-6 free base]]
• Biozol Catalog Number: AMO-M31223
• Supplier Catalog Number: M31223
• Alternative Catalog Number: AMO-M31223-1MG
• Manufacturer: Abmole Bioscience
• Category: Biochemikalien

Product Description

BMSpep-57 hydrochloride is a potent and competitive macrocyclic peptide inhibitor of PD-1/PD-L1 interaction with an IC50 of 7.68 nM. BMSpep-57 hydrochloride binds to PD-L1 with Kds of 19 nM and 19.88 nM in MST and SPR assays, respectively. BMSpep-57 hydrochloride facilitates T cell function by in creasing IL-2 production in PBMCs.

Product Properties

• Molecular Weight: 1904.63
• Purity: 99.0%
• CAS Number: [1629655-80-6 free base]
• Formula: C89H127ClN24O19S
• Target: PD-1/PD-L1