KRN 633 is an ATP-competitive inhibitor of VEGFR1/2/3 with IC50 of 170 nM/160 nM/125 nM, weakly inhibits PDGFR-alpha/beta and c-Kit, does not block the phosphorylation of FGFR-1, EGFR or c-Met in cell.
Molecular Weight:
416.86
Purity:
>99.0%
CAS Number:
[286370-15-8]
Formula:
C20H21ClN4O4
Target:
VEGFR/PDGFR
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