AR-42 is an HDAC inhibitor with IC50 of 30 nM. AR-42 induces growth inhibition, cell-cycle arrest, apoptosis, and activation of caspases-3/7. AR-42 promotes hyperacetylation of H3, H4, and alpha-tubulin, and up-regulation of p21.
Molecular Weight:
312.36
Purity:
99.98%
CAS Number:
[935881-37-1]
Formula:
C18H20N2O3
Target:
HDAC
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