Propafenone HCl is a sodium-channel blocker that also has a high affinity for beta-receptors (IC50 = 32 nM). It blocks transient outward potassium current (Ito) and sustained delayed rectifier K+ current (Isus) with IC50 values of 4.9 µM and 8.6 µM, respectively.In addition, Propafenone inhibits the proliferation of esophageal cancer by inducing mitochondrial dysfunction and apoptosis.
Molecular Weight:
377.9
Purity:
>99.0%
CAS Number:
[34183-22-7]
Formula:
C21H27NO3.HCl
Target:
Sodium Channel
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