Flavopiridol competes with ATP to inhibit CDKs including CDK1, CDK2, CDK4 and CDK6 with IC50 of ~ 40 nM. It is 7.5-fold more selective for CDK1/2/4/6 than CDK7. Flavopiridol is initially found to inhibit EGFR and PKA.
Molecular Weight:
438.3
Purity:
>99.0%
CAS Number:
[131740-09-5]
Formula:
C21H20ClNO5.HCl
Target:
CDK
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