NPS-2143 is a novel potent and selective antagonist of Ca(2+) receptor with IC50 of 43 nM. NPS-2143 (SB-262470A) blocks increases in cytoplasmic Ca2+ concentrations (IC50=43 nM) elicited by activating the Ca2+ receptor in HEK 293 cells expressing the human Ca2+ receptor.
Molecular Weight:
408.92
Purity:
>99.0%
CAS Number:
[284035-33-2]
Formula:
C24H25ClN2O2
Target:
Calcium-sensing Receptor
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