MK-2461 is a potent, multi-targeted inhibitor for c-Met(WT/mutants) with IC50 of 0.4-2.5 nM, less potent to Ron, Flt1, 8- to 30-fold greater selectivity of c-Met targets versus FGFR1, FGFR2, FGFR3, PDGFRbeta, KDR, Flt3, Flt4, TrkA, and TrkB.
Molecular Weight:
495.55
Purity:
>99.0%
CAS Number:
[917879-39-1]
Formula:
C24H25N5O5S
Target:
c-Met
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