MK-5108 (VX-689) is a highly selective Aurora A inhibitor with IC50 of 0.064 nM and is 220- and 190-fold more selective for Aurora A than Aurora B/C, while it inhibits TrkA with less than 100-fold selectivity.
Molecular Weight:
461.94
Purity:
>99.0%
CAS Number:
[1010085-13-8]
Formula:
C22H21ClFN3O3S
Target:
Aurora Kinase
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