Belnacasan (VX-765) is a potent and selective inhibitor of caspase-1 with Ki of 0.8 nM. Belnacasan (VX-765) inhibits the release of LPS-induced IL-1beta and IL-18 by human PBMCs with an IC50 of ~0.7 µM.
Molecular Weight:
509
Purity:
99.68%
CAS Number:
[273404-37-8]
Formula:
C24H33ClN4O6
Target:
Caspase
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