Begacestat selectively inhibits cleavage of amyloid precursor protein (APP) over Notch. Lowers levels of Abeta42 and Abeta40 (EC50 values are 12.4 and 14.8 nM respectively in cells expressing human recombinant APP).
Molecular Weight:
391.74
Purity:
>99%
CAS Number:
[769169-27-9]
Formula:
C9H8ClF6NO3S2
Target:
Gamma-secretase/Beta-secretase
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