Pyridone 6 is a potent, reversible, cell-permeable, and ATP-competitive inhibitor of JAK1 (IC50 = 15 nM for murine JAK1), JAK2 (IC50 = 1 nM), JAK3 (Ki = 5 nM), and Tyk 2 (IC50 = 1 nM) (Janus protein tyrosine kinases).
Molecular Weight:
309.34
Purity:
98.84%
CAS Number:
[457081-03-7]
Formula:
C18H16FN3O
Target:
JAK
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