Sophocarpine monohydrate, CAS [[145572-44-7]]

Catalog Number: AMO-M3913
Article Name: Sophocarpine monohydrate, CAS [[145572-44-7]]
Biozol Catalog Number: AMO-M3913
Supplier Catalog Number: M3913
Alternative Catalog Number: AMO-M3913-5MG,AMO-M3913-10MG,AMO-M3913-20MG,AMO-M3913-50MG
Manufacturer: Abmole Bioscience
Category: Biochemikalien
Sophocarpine monohydrate is a HERG K+ channel blocker with IC50 of 100-300 µM and Na+ channel inward current inhibitor. Sophocarpine monohydrate is a PTEN activator and an inhibitor of PI3K/Akt, MEK/ERK, and NF-kappaB signaling pathways. Sophocarpine monohydrate upregulates PTEN expression and inhibits PI3K/Akt phosphorylation, arrests tumor cell cycle and induces apoptosis. Sophocarpine monohydrate inhibits MEK/ERK phosphorylation and VEGF secretion, reducing tumor cell migration.
Molecular Weight: 264.36
Purity: >99.0%
CAS Number: [145572-44-7]
Formula: C15H24N2O2
Target: Autophagy