Eurycomalactone is a potent NF-kappaB inhibitor with an IC50 value of 0.5 µM. Eurycomalactone inhibits protein synthesis and depletes cyclin D1. Eurycomalactone enhances radiosensitivity through arrest cell cycle at G2/M phase and delayed DNA double-strand break repair.
Molecular Weight:
348.39
Purity:
>98.5%
CAS Number:
[23062-24-0]
Formula:
C19H24O6
Target:
NF-kappaB
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